Wilson’s Disease is an autosomal recessive genetic disease that was first reported more than a century ago. Our knowledge about the disease has since flourished and we now know the in and outs of this infrequent, but not rare disease very well, including treatment of both forms of the disease affecting the liver and the brain. This disease results from accumulation of excess copper in liver and/or brain. Diagnosis may be difficult due to complex disease manifestations. 24-hour urinary copper estimation remains the mainstay of diagnosing Wilson’s disease. If untreated, the prognosis is poor. However, there are excellent treatment options for Wilson’s disease these days including liver transplantation. Strong clinical suspicion and extensive investigation are important for diagnosis of Wilson’s disease. It is therefore important to share experience about individual cases of Wilson’s disease in scientific literature to keep peers continuously updated about the varied presentation of this life-threatening condition. Here we report 3 recent cases of adult Wilson’s liver disease as well as review of published literature from Bangladesh.