Atopic March; Revisited

Authors: Enas Attia*

Received: 2024-06-01 | Accepted: 2024-06-13 | Published: 2024-06-21 | Views: 44

DOI: https://dx.doi.org/10.46527/2583-6374.157

Abstract
Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease characterized by recurrent eczematous skin lesions
and intense itching. Globally, it affects 10%-30% of children and 2%-10% of adults, with a two- to three-fold increase in
prevalence noted over the last decades [1]. AD pathogenesis is multifactorial, and involves a complex interaction between
environmental factors, genetics, the immune system, and other factors such as microbiome, which contribute to skin barrier
dysfunction and inflammation [2-4].